The conference, scheduled for December 6th–8th, 2027, in Hefei, China, will focus on the latest research in the field of the Industrial Internet of Intelligence. It aims to build a face-to-face platform for experts, scholars and researchers from universities, research institutes and industries at home and abroad to exchange experience and present the latest research findings. Through in-depth academic discussions and industry exchanges, participants can showcase state-of-the-art scientific and technological achievements, share research insights, explore cooperation opportunities and advance the interdisciplinary development of industrial intelligent networking, industrial data and digital models, industrial large models, industrial agents and autonomous systems, integrated applications of industrial internet of intelligence, as well as industrial security and trustworthiness, covering key areas including industrial 6G/5G private networks, digital twins, intelligent manufacturing, human-machine integration and industrial network security.